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论著.文献计量学研究 | 更新时间:2025-01-21
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基于文献计量学分析国内近30年中医药治疗胃癌的研究现状、热点及趋势
Research current status, hotspots and trends of Traditional Chinese Medicine for the treatment of gastric cancer in the past 30 years in China based on bibliometrics: an analytic study

广西医学 页码:1920-1928

作者机构:熊常州,在读博士研究生,研究方向为胃癌的中医药防治。

基金信息:国家自然科学基金项目(82360959);广西自然科学基金项目(2024GXNSFDA010021、2024GXNSFBA010160);广西高校中青年教师科研基础能力提升项目(2023KY0297)

DOI:10.11675/j.issn.0253⁃4304.2024.12.17

  • 中文简介
  • 英文简介
  • 参考文献

目的 基于文献计量学分析国内近30年中医药治疗胃癌的研究现状、热点及趋势。方法 检索中国知网1993年1月1日至2023年9月1日中医药治疗胃癌的相关文献,采用Microsoft Excel 2019软件进行统计描述,绘制相关文献发文量年份变化趋势折线图。采用CiteSpace软件和VOSviewer软件分析作者发文量和研究机构发文量并进行共现网络分析,对关键词进行共现、聚类和突现分析。结果  1993—2023年,中国知网收录的中医药治疗胃癌相关文献共444篇,年度发文量总体呈波动上升趋势,形成多个核心团队及研究机构群,主要有南京、北京和上海三大合作网络,发文量排名前3的研究机构是南京中医药大学、江苏省中医院、北京中医药大学东直门医院,发文量排名前3的作者为侯丽、刘沈林、陈国忠。关键词共1 438个,出现频次最高的关键词是胃癌,其次是中医药、细胞凋亡及名医经验。关键词可形成10个聚类,分别为中医药、中医证型、细胞凋亡、名医经验、细胞侵袭、临床研究、化疗、四君子汤、微调平衡、抑瘤率。关键词突现分析结果显示细胞侵袭、名医经验、免疫功能、数据挖掘、分子对接是中医药治疗胃癌研究领域主要的研究热点和未来的研究趋势。结论 中医药治疗胃癌的研究热度总体呈现波动上升趋势,研究热点集中于细胞凋亡、化疗、免疫功能、名医经验、分子对接、数据挖掘等方面,中医经典名方验方和中药有效成分的现代生物信息学研究、名医对于胃癌病因病机和论治经验的探讨及挖掘,以及中医药对胃癌患者免疫功能的影响是该领域未来的研究趋势。

Objective To analyze the research current status, hotspots and trends of Traditional Chinese Medicine for the treatment of gastric cancer in the past 30 years in China based on bibliometrics. Methods Literature related to Traditional Chinese Medicine for the treatment of gastric cancer was retrieved from China National Knowledge Infrastructure from 1st January, 1993 to 1st September, 2023. The Microsoft Excel 2019 software was employed to perform statistical description. The line chart of annual variation trend of the number of relevant literature publications was drawn. The CiteSpace software and VOSviewer software were used to analyze the number of publications by authors and research institutions, to conduct co⁃occurrence network analysis, and to conduct co⁃occurrence, clustering and burstness analyses of keywords. Results From 1993 to 2023, a total of 444 literature related to the treatment of gastric cancer with Traditional Chinese Medicine was collected in China National Knowledge Infrastructure, and the annual number of publications revealed an overall fluctuating upward trend, forming multiple core teams and research institutions, mainly concerning 3 collaboration networks in terms of Nanjing, Beijing, and Shanghai, and Nanjing University of Chinese Medicine, Jiangsu Province Hospital of Chinese Medicine, and Dongzhimen Hospital of Beijing University of Chinese Medicine ranked the top three research institutions in terms of the number of publications. The top three authors of the number of publications were Hou Li, Liu Shenlin, and Chen Guozhong. There were 1438 keywords in total, and the most frequent keyword was gastric cancer, followed by Traditional Chinese Medicine, cell apoptosis, and experiences of famous doctors. The keywords could form 10 clusters, which were Traditional Chinese Medicine, Traditional Chinese Medicine syndrome type, cell apoptosis, famous doctor's experiences, cell invasion, clinical research, chemotherapy, Sijunzi Decoction, fine⁃tuning balance, and tumor inhibition rate. The results of keyword burstness analysis indicated that cell invasion, famous doctor's experiences, immune function, data mining and molecular docking were the recent main research hotspots and future research trends in the field of Traditional Chinese Medicine for the treatment of gastric cancer. Conclusion The research popularity of Traditional Chinese Medicine in the treatment of gastric cancer generally expresses a fluctuating upward trend, and the research hotspots focus on cell apoptosis, chemotherapy, immune function, experiences of famous doctors, molecular docking, data mining and other aspects. The modern bioinformatics research of Traditional Chinese Medicine classic prescriptions and effective components of Traditional Chinese Medicine, the exploration and mining of etiology and pathogenesis and treatment experiences on gastric cancer, as well as the influence of Traditional Chinese Medicine on immune function of patients with gastric cancer are the future research trends in this field.

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