广西医学

目的调查广西北部湾经济区居民的地中海贫血（以下简称地贫）筛查意愿，并分析其影响因素。方法采用方便抽样方法抽取广西北部湾经济区居民作为调查对象进行电子问卷调查，采用多因素Logistic回归模型和决策树模型分析居民地中海贫血筛查意愿的影响因素。结果共回收有效问卷12 708份，愿意参与地中海贫血筛查的比例为92.14%，地贫相关知识知晓情况得分为（26.06±5.65）分，地贫相关知识获取渠道主要为医院、学校等主题宣传（35.23%）。年龄、学历、职业、地贫相关知识知晓情况和地贫相关知识获取渠道是广西北部湾经济区居民地贫筛查意愿的影响因素（P<0.05）。结论广西北部湾经济区居民的地中海贫血筛查意愿相对较高，年龄、学历、职业、地贫相关知识知晓情况和地贫相关知识获取渠道是其地贫筛查意愿的影响因素。

Objective To investigate the willingness for thalassemia screening among residents in Guangxi Beibu Gulf Economic Zone, and to analyze its influencing factors. Methods A convenience sampling method was used to select residents in Guangxi Beibu Gulf Economic Zone for an electronic questionnaire survey. The multivariate Logistic regression model and decision tree model were employed to analyze factors influencing screening willingness of thalassemia. Results A total of 12 708 valid questionnaires were collected. The proportion of willingness for thalassemia screening was 92.14%, with awareness score of thalassemia-related knowledge in 26.06±5.65. Primary source-acquisition channels of thalassemia-related knowledge included hospital/school-based health campaigns (35.23%). Age, educational level, occupation, thalassemia-related knowledge, and thalassemia-related knowledge acquisition channels were the influencing factors for screening willingness of thalassemia among residents in Guangxi Beibu Gulf Economic Zone (P<0.05). Conclusions Residents in Guangxi Beibu Gulf Economic Zone demonstrate relatively high willingness for thalassemia screening. Age, educational level, occupation, thalassemia-related knowledge awareness status, and thalassemia-related knowledge acquisition channels are the influencing factors for their willingness for thalassemia screening.