广西医学

目的系统评价心脏康复对不稳定型心绞痛（UAP）患者的康复效果。方法计算机检索中国知网、万方数据知识服务平台、维普中文期刊服务平台、中国生物医学文献服务系统、The Cochrane Library、Embase、PubMed及Web of Science数据库中UAP患者心脏康复效果的相关文献。对文献进行筛选、资料提取和质量评价后，采用RevMan 5.3软件进行Meta分析。结果共纳入12篇文献，包含1 169例患者。Meta分析结果显示，与对照组相比，心脏康复能有效改善UAP患者的左室射血分数、纽约心脏病协会心功能分级、左心室舒张末期内径、收缩压、舒张压、峰值摄氧量和无氧阈，降低胆固醇、LDL、甘油三酯水平，降低再住院发生率和不良心血管事件发生率，但在改善UAP患者生活质量上未表现明显优势。结论心脏康复可以有效改善UAP患者的心功能、脂质代谢和峰值摄氧量等指标，降低患者的再住院发生率和不良心血管事件发生率，但在生活质量等方面的作用还需要进一步研究验证。

Objective To systematically evaluate the rehabilitation effect of cardiac rehabilitation in patients with unstable angina pectoris (UAP). Methods Relevant literature of cardiac rehabilitation effect in UAP patients was retrieved from the databases of China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, VIP, China Biology Medicine disc, The Cochrane Library, Embase, PubMed, and Web of Science. After literature screening, data extraction, and quality assessment, Meta⁃analysis was performed using the RevMan 5.3 software. Results A total of 12 literature involving 1169 patients was enrolled. Meta⁃analysis results demonstrated that compared with the control group, cardiac rehabilitation could effectively ameliorate left ventricular ejection fraction, New York Heart Association cardiac functional classification, left ventricular end⁃diastolic diameter, systolic blood pressure, diastolic blood pressure, peak oxygen uptake, and anaerobic threshold in UAP patients, and decreased total cholesterol, LDL, triglyceride levels, as well as decrease the incidence rates of rehospitalization and adverse cardiovascular events. However, cardiac rehabilitation exhibited no significant advantage in improving quality of life in UAP patients. Conclusion Cardiac rehabilitation can effectively ameliorate indices such as cardiac function, lipid metabolism, and peak oxygen uptake in UAP patients, decrease the incidence rates of rehospitalization and adverse cardiovascular events. However, its effects on quality of life require further studies to validate.

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