Objective To analyze the current status, hotspots, and trends in relevant research on Pseudomonas aeruginosa and chronic obstructive pulmonary disease (COPD) based on bibliometric methods. Methods Literature related to Pseudomonas aeruginosa and COPD from January 1, 2014, to June 30, 2024, was retrieved from the Web of Science Core Collection. Visual analysis and network knowledge mapping were performed using VOSviewer 1.6.20, CiteSpace 6.3.R1, and Co⁃Occurrence 14.9 software to examine the number of annual publications, contributing countries, research institutions, authors, journal distribution, and keywords. Results A total of 349 English⁃language articles were included. From 2014 to 2024, the number of annual publications of research on Pseudomonas aeruginosa and COPD generally showed an upward trend, peaking in 2022. The United States had the highest publication output, followed by China and Spain. The United States had the most extensive international collaborations, followed by Spain and England. The top three research institutions in terms of number of publications were all located in Spain: the University of Barcelona, the Autonomous University of Barcelona, and the La Fe University and Polytechnic Hospital, respectively. The literature involved 2371 authors, with 90 core authors. The top three authors in terms of number of publications were Martinez⁃Garcia MA, De La Rosa D, and Chalmers JD. Among them, Martinez⁃Garcia MA and De La Rosa D from Spain formed the largest collaborative author network. A total of 170 academic journals published relevant research on Pseudomonas aeruginosa and COPD. The International Journal of Chronic Obstructive Pulmonary Disease was the most influential journal in disseminating research findings in this field, followed by PLOS One. The paper Pseudomonas aeruginosa in patients hospitalised for COPD exacerbation: a prospective study authored by Garcia⁃Vidal C (2009) received the highest citation count. Research hotspots in the field of Pseudomonas aeruginosa and COPD included airway inflammation, COPD exacerbation, microbiome, phenotypes, comorbidities, chronic bronchial infection, host⁃pathogen interactions, and antibiotic resistance. Comorbidities (bronchiectasis, lung cancer), antibiotic resistance, chronic bronchial infection, drug delivery, and nanoparticles represented emerging research trends in this area. Conclusion Research interest in Pseudomonas aeruginosa and COPD remains high overall. The United States, Spain, and China lead this field, with Spain hosting the most authoritative research institutions and core author teams. However, there is limited collaboration between domestic and international research institutions. Future research should focus on strengthening international collaborations. Comorbidities in COPD, antibiotic resistance, chronic bronchial infection, and novel nanoparticle⁃based drug delivery systems represent emerging research hotspots in this field.

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