广西医学

目的基于CiteSpace软件探讨中医药治疗多囊卵巢综合征（PCOS）的研究现状、热点和趋势。方法检索中国知网、PubMed数据库2000—2023年收录的中医药治疗PCOS的相关文献。采用NoteExpress V3.X软件管理文献，采用WPS Office软件统计数据，采用CiteSpace 6.1.R6软件对文献的年度发文量、发文期刊、发文作者、发文机构、关键词等进行可视化分析。结果共纳入中文文献885篇、英文文献56篇。2000—2023年，中医药治疗PCOS相关文献的年度发文量总体呈上升趋势。中文文献发表于227本中文期刊，其中《河北中医》发文量最多（28篇），英文文献发表于35本英文期刊，其中Journal of Ethnopharmacology发文量最多（9篇）。中文文献共有2 040位作者，核心作者126位，核心作者发文量252篇，作者间合作密度低，未形成核心作者群；英文文献共311位作者，核心作者39位，核心作者发文量24篇，作者间合作密度偏低，也未形成核心作者群。中文文献发文量前3的研究机构为南京中医药大学（23篇）、广州中医药大学第一附属医院（20篇）、黑龙江中医药大学附属第一医院（18篇），英文文献发文量前3的研究机构是Kyung Hee University（庆熙大学，3篇）、Chengdu University of Traditional Chinese Medicine（成都中医药大学，3篇）及Women's Hospital School of Medicine Zhejiang University（浙江大学医学院附属妇产科医院，3篇）。目前该领域研究热点为PCOS及相关疾病诊治方法的探索与优化、相关机制研究，未来研究趋势主要包括数据挖掘、用药规律、肠道菌群、network pharmacology（网络药理学）、molecular docking（分子对接）等。结论中医药治疗PCOS具有独特优势，国内外相关研究呈阶段性增长，作者间合作密度偏低，尚未形成核心作者群，且鲜有跨地域交流。目前研究聚焦于PCOS及相关并发症的发病机制与治疗，未来也将以分子机制为重点进一步深入探索。

Objective To explore the current research status, hotspots, and trends of Traditional Chinese Medicine for the treatment of polycystic ovary syndrome (PCOS) based on CiteSpace software. Methods Literature related to Traditional Chinese Medicine for the treatment of PCOS from 2000 to 2023 was retrieved from the China National Knowledge Infrastructure and PubMed databases. NoteExpress V3.X software was used for literature management, WPS Office software for data statistics, and CiteSpace 6.1.R6 software for visual analysis of number of annual publication, and publishing journals, authors, institutions, as well as keywords. Results A total of 885 Chinese articles and 56 English articles were included. From 2000 to 2023, the number of annual publication of literature on Traditional Chinese Medicine for treating PCOS revealed an overall upward trend. Chinese articles were published in 227 Chinese journals, with Hebei Journal of Traditional Chinese Medicine having the most publications (28 articles). English articles were published in 35 English journals, with Journal of Ethnopharmacology having the most publications (9 articles). The Chinese literature involved 2040 authors, with 126 core authors who published 252 articles; the collaboration density among authors was low, and no core author group had formed. The English literature involved 311 authors, with 39 core authors who published 24 articles; collaboration density was also relatively low, and no core author group had formed. The top three research institutions for Chinese literature were Nanjing University of Chinese Medicine (23 articles), The First Affiliated Hospital of Guangzhou University of Chinese Medicine (20 articles), and The First Affiliated Hospital of Heilongjiang University of Chinese Medicine (18 articles). The top three research institutions for English literature were Kyung Hee University (3 articles), Chengdu University of Traditional Chinese Medicine (3 articles), and Women's Hospital School of Medicine Zhejiang University (3 articles). Current research hotspots in this field included the exploration and optimization of diagnosis and treatment methods for PCOS and related diseases, and related mechanism studies. Future research trends mainly include data mining, medication rules, gut microbiota, network pharmacology, and molecular docking, etc. Conclusion Traditional Chinese Medicine has unique advantages for treating PCOS. Relevant research, both domestically and internationally, has shown phased growth. However, collaboration density among authors is relatively low, a core author group has not yet formed, and cross⁃regional communication is rare. Current research focuses on the pathogenesis and treatment of PCOS and its related complications. Future research will further explore these areas with a focus on molecular mechanisms.