广西医学

目的探讨脑卒中患者经济毒性现状及其影响因素。方法选取244例脑卒中患者作为研究对象，采用一般资料调查表、患者报告结局的经济毒性综合评分（COST⁃PROM）量表、康复治疗依从性评价表对其进行调查。比较不同特征患者的COST⁃PROM量表总分，并分析患者康复治疗依从性评价表总分与COST⁃PROM量表总分的相关性。采用多元线性回归模型分析脑卒中患者经济毒性的影响因素。结果共发放244份调查问卷，回收有效问卷230份，回收有效率为94.26%。脑卒中患者COST⁃PROM量表总分为（24.16±5.49）分，经济毒性发生率为78.70%。不同年龄、居住地、家庭人均月收入、脑卒中发作次数、病情严重程度、康复治疗时间及康复治疗依从性的脑卒中患者之间的COST⁃PROM量表总分比较，差异有统计学意义（P<0.05）。COST⁃PROM量表总分与康复治疗依从性评价表总分呈正相关（P<0.05）。多元线性回归分析结果显示，年龄、居住地、家庭人均月收入、脑卒中发作次数、病情严重程度、康复治疗时间及康复治疗依从性是脑卒中患者经济毒性的影响因素（P<0.05）。结论脑卒中患者普遍存在经济毒性，年龄、居住地、家庭人均月收入、脑卒中发作次数、病情严重程度、康复治疗时间及康复治疗依从性是脑卒中患者经济毒性的影响因素。

Objective To explore the current status of financial toxicity in patients with cerebral stroke and its influencing factors. Methods A total of 244 patients with cerebral stroke were selected as the research subjects, and they were investigated with the general information questionnaire, Comprehensive Scores for Financial Toxicity Based on the Patient⁃Reported Outcome Measure (COST⁃PROM) scale, and rehabilitation treatment compliance evaluation scale. The total score of COST⁃PROM scale was compared between patients with different characteristics, and the correlation between the total score of rehabilitation treatment compliance evaluation scale of patients and the total score of COST⁃PROM scale was analyzed. The multiple linear regression model was adopted to analyze the influencing factors for financial toxicity in patients with cerebral stroke. Results A total of 244 investigation questionnaires were distributed and 230 valid questionnaires were collected, with an effective recovery rate of 94.26%. The total score of COST⁃PROM scale for patients with cerebral stroke was 24.16±5.49, and the incidence rate of financial toxicity was 78.70%. There were statistically significant differences in the total score of COST⁃PROM scale between cerebral stroke patients with different ages, residences, per capita monthly income of the family, number of stroke episodes, disease severity, rehabilitation treatment time and rehabilitation treatment compliance (P<0.05). The total score of COST⁃PROM scale positively correlated with the total score of rehabilitation treatment compliance evaluation scale (P<0.05). The results of multiple linear regression analysis revealed that age, residence, per capita monthly income of the family, number of stroke episodes, disease severity, rehabilitation treatment time and rehabilitation treatment compliance were the influencing factors for financial toxicity in patients with cerebral stroke (P<0.05). Conclusion Financial toxicity is common in patients with cerebral stroke. Age, residence, per capita monthly income of the family, number of stroke episodes, disease severity, rehabilitation treatment time and rehabilitation treatment compliance are the influencing factors for financial toxicity in patients with cerebral stroke.