Objective To conduct a visual analysis of domestic and international literature on myocardial energy metabolism over the past 30 years, aiming to outline the research status, hotspots, and frontier trends in this field. Methods Literature related to myocardial energy metabolism was searched and screened from databases including China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, VIP, China Biomedical Literature Service System, PubMed, and Web of Science Core Collection. Microsoft Excel software was used for statistical analysis of publication volume and journals. CiteSpace software was employed for author co⁃occurrence analysis, and keyword co⁃occurrence, clustering, timeline mapping, and burst detection analyses. Results A total of 3906 Chinese articles and 3445 English articles were included. The overall publication volume for both languages depicted an upward trend. Chinese publications were dispersed across multiple disciplines such as pathophysiology and clinical medicine, while English publications were predominantly found in top⁃tier international basic and clinical journals. There were 187 core authors for Chinese literature and 104 for English literature, forming multiple research teams centered around figures such as Zhu Mingjun and Dyck Jason RB. Keyword co⁃occurrence and cluster analyses indicated that research hotspots focused on diseases such as heart failure, myocardial infarction, myocardial ischemia/reperfusion injury, diabetic cardiomyopathy, as well as mechanisms involving abnormal mitochondrial structure and function, oxidative stress, and gene expression. Metabolic drugs (e.g., trimetazidine, levocarnitine) and Traditional Chinese Medicine (e.g., Astragalus membranaceus, Salvia miltiorrhiza) interventions accounted for a higher proportion in Chinese research. The integrated application of imaging techniques, omics technologies, and bioinformatics methods served as a core driver advancing the field. Burst term analysis suggested that future research would focus on reviews, mechanisms of Traditional Chinese Medicine, network pharmacology, mitochondrial dynamics, and inflammatory responses. Conclusion Research on myocardial energy metabolism has entered a stage of systematic integration and mechanism deepening. Future efforts should strengthen interdisciplinary collaboration and international exchange, summarize existing research findings, explore the mechanisms of Traditional Chinese Medicine, focus on mitochondrial function and the interaction between inflammation and metabolism, promote the translation of basic research to clinical applications, and provide more evidence to support myocardial metabolic therapies.

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