广西医学

目的探讨结直肠息肉发生的影响因素。方法回顾性分析完成结肠镜检查的839例体检者的临床资料，根据是否有结直肠息肉分为结直肠息肉组与对照组。比较两组的临床资料、空腹血脂和血糖指标，采用多因素Logistic回归模型分析结直肠息肉形成的影响因素，并分析其与结直肠息肉病理类型和数量的相关性。结果 839例完成结肠镜检查的体检者中，检出结直肠息肉者332例（39.57%），其中息肉数量≥3颗者57例（17.17%），息肉数量<3颗者275例（82.83%）；病理类型为腺瘤性息肉者110例（33.13%），非腺瘤性息肉者222例（66.87%）。结直肠息肉组患者的年龄、男性比例、体重、体质指数、腰围、腰臀比、腰高比、合并高血压的比例、甘油三酯（TG）、LDL⁃C/HDL⁃C、总胆固醇（TC）/HDL⁃C、TG/LDL⁃C、TG/HDL⁃C、空腹血糖高于对照组，TC/TG低于对照组（P<0.05）。多因素Logistic回归分析结果显示，年龄、腰高比和空腹血糖是结直肠息肉形成的影响因素（P<0.05），而上述影响因素与结直肠息肉的病理类型和数量无明显相关（P>0.05）。结论年龄、腰高比和空腹血糖是结直肠息肉形成的影响因素。

Objective To investigate the influencing factors for the occurrence of colorectal polyps. Methods A retrospective analysis of clinical data from 839 check⁃up individuals who had completed colonoscopic examination was conducted. According to the presence of colorectal polyps, individuals were assigned to colorectal polyp group or control group. The clinical data, fasting blood lipid and blood glucose indices of the two groups were compared. The multivariate Logistic regression model was used to analyze the influencing factors for colorectal polyp formation, and its correlation with pathological pattern and number of colorectal polyps was analyzed. Results Among 839 check⁃up individuals who completed colonoscopic examination, 332 (39.57%) were found to have colorectal polyps, among whom 57 (17.17%) had ≥3 polyps and 275 (82.83%) had less than 3 polyps. There were 110 cases (33.13%) with pathological pattern of adenomatous polyps and 222 cases (66.87%) of non⁃adenomatous polyps. Age, male proportion, weight, body mass index, waist circumference, waist⁃to⁃hip ratio, waist⁃to⁃height ratio, proportion of concomitant hypertension, triglycerid (TG), LDL⁃C/HDL⁃C, total cholesterol (TC)/HDL⁃C, TG/LDL⁃C, TG/HDL⁃C, and fasting blood glucose of the colorectal polyps group were higher than those of the control group, and TC/TG was lower than that of the control group (P<0.05). The results of multivariate Logistic regression analysis revealed that age, waist⁃to⁃height ratio, and fasting blood glucose were the influencing factors for the formation of colorectal polyps (P<0.05), whereas there was no significant correlation between the aforementioned influencing factors and pathological pattern and number of colorectal polyps (P>0.05). Conclusion Age, waist⁃to⁃height ratio, and fasting blood glucose are the influencing factors for colorectal polyps formation.

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