Children with chronic kidney disease (CKD) may have endocrine hormone levels disorders, which may cause complications such as hyperparathyroidism, hypothyroidism, growth retardation, delayed puberty, insulin resistance, anemia, bone diseases, and cardiovascular diseases. This paper reviews CKD and concomitant diseases related to hypothalamic⁃anterior pituitary hormone axis insufficiency in children, mainly including hypothyroidism, growth retardation, adrenocortical insufficiency, and delayed puberty, etc., aiming at providing a reference for the comprehensive management of children with CKD.

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