Premature ovarian insufficiency (POI) is a disease seriously affecting female reproductive health, which is mainly manifested as menstrual disorder and decreased fertility due to diminished ovarian functions before 40 years old; in addition, its treatment and management have received extensive attention. Traditional Chinese Medicine has unique advantages in the treatment of POI. Through a variety of treatment methods such as internal treatment, external treatment and combined therapy, as well as the diagnosis and treatment strategy combined with modern medicine, Traditional Chinese Medicine provides a more comprehensive and personalized treatment regimen for POI patients, which not only effectively ameliorates ovarian function and fertility of patients, but also improves the overall health level and quality of life in patients. This paper reviews the latest progress of Traditional Chinese Medicine in the treatment of POI in recent years, including the application of Traditional Chinese Medicine in regulating the hormone level of reproductive endocrine system, improving ovarian reserve function, ameliorating endometrial receptivity, optimizing assisted reproductive treatment, and a variety of external treatments of Traditional Chinese Medicine, aiming at further improving treatment strategy of POI by using the unique advantages of Traditional Chinese Medicine.

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