Hypoxemic respiratory failure (HRF) and pulmonary hypertension (PH) in preterm infants are important causes of neonatal death and complications. In recent years, with the in⁃depth understanding of the different classifications and phenotypes of HRF/PH, the correct diagnosis and the selection of targeted intervention strategies for different phenotypes have become more and more standardized. In particular, the optimization of respiratory support strategies and targeted therapy based on inhaled nitric oxide have shown their prospects. However, for the special population of preterm infants, more clinical evidence still needs to be accumulated for the management of PH. This paper focuses on the research progress on the diagnosis and treatment of acute PH and bronchopulmonary dysplasia associated with PH in preterm infants, aiming at providing reference for the management of PH in preterm infants.

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