富血小板血浆(PRP)是一种富含多种生物活性因子的自体生物制剂。在卵巢功能方面,PRP有助于改善生殖内分泌激素水平,促进卵泡发育;在子宫内膜方面,PRP可增加子宫内膜厚度与容受性,改善慢性炎症状态。因此,PRP在与女性不孕症相关的各类疾病治疗中展现出巨大的应用潜力。本文系统综述了PRP在卵巢储备功能减退、多囊卵巢综合征、宫腔粘连、慢性子宫内膜炎、反复种植失败等女性不孕症相关疾病中的应用进展,分析其相关作用机制,旨在推动PRP在生殖医学中的规范化应用。
富血小板血浆(PRP)是一种富含多种生物活性因子的自体生物制剂。在卵巢功能方面,PRP有助于改善生殖内分泌激素水平,促进卵泡发育;在子宫内膜方面,PRP可增加子宫内膜厚度与容受性,改善慢性炎症状态。因此,PRP在与女性不孕症相关的各类疾病治疗中展现出巨大的应用潜力。本文系统综述了PRP在卵巢储备功能减退、多囊卵巢综合征、宫腔粘连、慢性子宫内膜炎、反复种植失败等女性不孕症相关疾病中的应用进展,分析其相关作用机制,旨在推动PRP在生殖医学中的规范化应用。
Platelet⁃rich plasma (PRP) is an autologous biological preparation rich in multiple bioactive factors. In terms of ovarian function, PRP helps improve reproductive endocrine hormone levels and promotes follicular development. Regarding the endometrium, PRP can increase endometrial thickness and receptivity while ameliorating chronic inflammatory conditions. Therefore, PRP demonstrates significant potential in treating various diseases associated with female infertility. This article systematically reviews progress in PRP applications for female infertility⁃related diseases such as diminished ovarian reserve, polycystic ovary syndrome, intrauterine adhesions, chronic endometritis, and repeated implantation failure, analyzing its underlying mechanisms to promote standardized use of PRP in reproductive medicine.