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女性生育力保存技术的研究进展
Research progress on female fertility preservation technology

广西医学 页码:1571-1577

作者机构:吴雨茵,硕士,研究方向为生殖医学。

基金信息:南宁市科学研究与技术开发计划项目(20253037);南宁市江南区科学研究与技术开发计划项目(20240826-09、20250919-09)

DOI:10.11675/j.issn.0253⁃4304.2025.11.06

  • 中文简介
  • 英文简介
  • 参考文献

随着癌症治疗水平提升、社会生育观念转变及全球育龄人群生育力下降趋势显现,生育力保存技术已成为生殖医学领域的核心议题。我国在该领域发展迅速,多项技术已达到国际先进水平。生育力保存技术的进步为面临生育风险女性提供了更多的选择,但未来仍需要进一步提高保存成功率并降低风险,还需严格遵循伦理原则,充分保障患者及其子代的健康权益。尽管伦理与法规挑战仍是女性生育力保存技术普及的关键瓶颈,但国际合作与持续创新为女性生育力保存技术的个性化与可及性提供了新的路径。本文就卵母细胞冷冻保存技术、卵巢组织冷冻保存技术及卵母细胞体外成熟技术等女性生育力保存技术的研究进展进行综述,以期为该领域的研究提供参考。

With advances in cancer treatment, evolving societal attitudes toward fertility, and a global trend of declining fertility among people of reproductive age, fertility preservation technologies have become a central focus in reproductive medicine. China has made rapid progress in this field, with several technologies now at internationally advanced levels. These advancements offer more options for women facing fertility risk; however, future efforts are still needed to improve success rates and reduce risks. It is also essential to strictly adhere to ethical principles to fully protect the health rights of patients and their offspring. Although ethical and regulatory challenges remain key bottlenecks in the widespread adoption of female fertility preservation, international cooperation and continuous innovation provide new pathways for personalized and accessible solutions of female fertility preservation. This article reviews research progress on female fertility preservation technologies, including oocyte cryopreservation, ovarian tissue cryopreservation, and in vitro maturation, aiming to offer insights for further studies in this area.

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