The joint construction of the China⁃ASEAN “Health Silk Road” serves as a vital practical embodiment of the Belt and Road Initiative in the health sector. As its core spiritual essence, medical humanities provide value guidance and practical support for building a community of shared health for mankind. Drawing on the practical experience of Guangxi Medical University in deepening China⁃ASEAN health cooperation, this paper analyzes the core significance of medical humanities in the development of the “Health Silk Road” from three dimensions: conceptual integration, shared values, and regional roles. Taking into account the humanistic particularities including cultural, ethical, and practical levels of ASEAN countries, the paper systematically examines the university's practical pathways for advancing medical humanities through three major dimensions: “humanistic education”, “life protection”, and “smart health”. It also analyzes the current challenges in practicing medical humanities within the framework of jointly building the China⁃ASEAN “Health Silk Road”. Finally, the paper proposes future directions for development, including expanding areas, optimizing systems, elevating education, and leading through evaluation, aiming to provide theoretical references and practical models for deepening China⁃ASEAN medical humanities cooperation and advancing the construction of a global community of health for all.  

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