ObjectiveTo explore the diagnostic value of 3.0T dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) combined with diffusion weighted imaging (DWI) for pathological staging of cervical cancer. MethodsA total of 70 patients with cervical cancer were selected as study group, and another 50 individuals who conducted gynecological routine examination and were excluded from cervical carcinogenesis during the same period were selected as control group. Both groups received routine MRI plain scan, DWI scan, and DCE-MRI scan for obtaining apparent diffusion coefficient (ADC), capacity transfer constant (Ktrans), rate constant (Kep), and extravascular extracellular volume fraction (Ve). Kep, Ktrans, Ve, and ADC were compared between the study group and the control group, and between patients with cervical cancer in different pathological staging. With postoperative pathological biopsy result as the gold standard, the diagnostic value of 3.0T DCE-MRI combined with DWI for pathological staging of cervical cancer was analyzed. ResultsThe study group exhibited lower ADC, whereas higher Kep, Ktrans, and Ve as compared with the control group (P＜0.05). With the severity increase of pathological staging of cervical cancer, ADC was gradually decreased, while Kep, Ktrans, and Ve were gradually elevated (P＜0.05). 3.0T DCE-MRI combined with DWI for the diagnosis of cervical cancer pathological staging results was relatively highly consistent with the results of postoperative pathological biopsy of cervical cancer (Kappa value=0.871, P=0.043, 95% CI: 0.787，0.955). Conclusion3.0T DCE-MRI combined with DWI exerts a relatively high diagnostic value for pathological staging of cervical cancer. According to the diagnostic results, timely treatment measures can be taken to control patients′ disease condition, so as to ameliorate patients′ prognosis.

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